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Case Series/Study
Diabetic foot ulcers (DFUs) treated following the correction of blood quality, blood quantity, associated comorbidities, bone lesions, previous foot surgery and tissue loss. We tried dressings, and *proprietary natural herbal cream in 65 patients and observed the healing outcomes.
Results: It is noted that most patients receiving dressing as part of standard care still encountered stalled healing in general. 20 patients received the *wound optimization cream containing proprietary herbal substances have been noted with faster and scarless healing. Four of the 20 patients were having Wagner grade 3 DFUs and received surgery to remove osteomyelitis for etiological factor correction. Their post-surgical wound size ranged between 30 cm2 to 150 cm2. The largest ulcer of 150 cm2 was in combined treatment of negative pressure wound therapy and *wound optimization cream for 2 weeks for size reduction and continued *wound optimization cream to reach complete wound closure in next 5 weeks. 2 ulcers only received this cream for healing in 5 and 13 weeks. The last ulcer with 108 cm2 with tendon and bone expose post-surgery received * wound optimization cream to promote granulation tissue growth. We saw the tendon and bone were fully covered by healthy granulation tissue in 4 weeks and we closed the wound by skin grafting. The remaining 16 patients were having Wagner grade 2 DFUs treated with *wound optimization cream and reached complete wound closure in 2 to 6 weeks.
Discussion: It is notable that the *wound optimization cream is able to promote tissue repair in our case collection which corresponds to its previously reported randomized controlled trial with 236 subjects of DFUs. We also saw no over-growth of fibrosis by the cream which leads to scarless healing. Interestingly, the *cream reported to have mechanism of action in regulating macrophages seems to fit in our practice to achieve rapid and satisfactory limb salvage.