(PI-024) The Efficacy and Advantages of Hypochlorous Acid Solution in Skin Grafting Procedures
Thursday, May 16, 2024
7:30 PM – 8:30 PM East Coast USA Time
Introduction: Skin grafting plays a pivotal role in reconstructive and burn surgery, addressing extensive skin loss resulting from various injuries. A recent addition to traditional skin grafting methods is the use of pure hypochlorous acid (HOCl) preserved solution. This solution has shown promise in preparing wound beds, particularly in cases with highly resistant microbiomes. Its efficacy lies in supporting the healing of skin grafts despite bacterial colonization, owing to its non-cytotoxic nature and physiological pH.
Methods: This abstract provides an overview of HOCl solution's application in skin grafting, focusing on its utilization in patients with burns, trauma, and necrotizing fasciitis. The potent antimicrobial activity of HOCl against a broad spectrum of pathogens creates an optimal environment for successful skin graft integration by eliminating microbial colonies and debris. Additionally, its anti-inflammatory properties contribute to reducing graft site inflammation, thereby expediting the wound healing process. This abstract will provide insight into application methods and conjunctive therapies to be utilized with skin grafting procedures.
Results: In this study involving 14 patients (6 women and 8 men) diagnosed with conditions including necrotizing fasciitis, Fournier’s gangrene, burns, trauma, hidradenitis suppurativa, and pressure injuries, all patients exhibited successful skin graft take.
Discussion: The incorporation of hypochlorous acid solution represents a significant advancement in graft management, effectively enhancing the success and efficacy of skin grafting procedures while positively impacting patient outcomes. Nonetheless, further research and clinical trials are imperative to optimize and refine its application in the realm of reconstructive surgery.