Case Series/Study
Hard-to-heal wounds often exhibit reduced tissue oxygen levels (Jain et al. 2006). Hyperbaric Oxygen Therapy (HBOT) has demonstrated the ability to enhance oxygen supply to such wounds, promoting healing. Transcutaneous Oximetry (TcPO2) has been employed for patient selection and monitoring treatment response during HBOT (Kaur et al. 2012; Bowen, Treadwell, and Goodwin 2016). However, TcPO2 has limitations, including variability in healthy individuals, sensitivity to positioning, and patient discomfort. This study explores the use of mobile multispectral near-infrared spectroscopy (NIRS) imaging to improve the assessment of HBOT efficacy in healing of diabetic foot ulcers (DFU).
Methods:
This study observed individuals in an outpatient setting who underwent Hyperbaric Oxygen Therapy (HBOT) for a DFU. An FDA-cleared hand-held mobile multispectral near infrared imaging device* was used to measure temperature and tissue oximetry. Prior to HBOT, multispectral near infrared images were collected. Once imaged, the individual then received HBO treatment. After treatment, the individual’s DFU was imaged again. Differences in tissue oximetry and temperature measurements between the images were measured to detect change.
Results:
The case series illustrates a significant enhancement in tissue oxygenation after HBOT, identifying patients with a potential to benefit from HBOT. Utilizing mobile multispectral NIRS imaging, particularly in diabetic foot ulcer cases, provides a powerful tool for showcasing therapeutic efficacy.
Discussion:
The findings underscore the versatility of mobile multispectral NIRS imaging in patient qualification for HBOT, documentation of therapeutic efficacy, and active patient engagement throughout their treatment journey. Mobile multispectral NIRS imaging emerges as a promising tool to refine and optimize HBOT programs, streamline clinical decision-making, enhance patient engagement, and contribute to the comprehensive documentation of therapeutic efficacy.
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