(CS-071) Use of Negative Pressure Wound Therapy with Instillation in Complex Wounds: A Small Case Series
Thursday, May 16, 2024
7:30 PM – 8:30 PM East Coast USA Time
Introduction: Negative pressure wound therapy (NPWT) with instillation and dwell time (NPWTi-d*) using a reticulated open cell foam dressing with through holes (ROCF-CC†) has been reported to help solubilize non-viable tissue and thick exudate as well as remove wound debris and infectious materials.1-3 The use of NPWTi-d with ROCF-CC was assessed in 8 patients with complex wounds.
Methods: Patients and wounds were assessed at presentation. Antibiotics were initiated as needed as well as surgical debridement. Exposed and delicate structures were protected with a non-adherent hydrofiber dressing. NPWTi-d with ROCF-CC were applied to the wounds. Normal saline, acetic acid (0.25%), or hypochlorous acid was instilled over the wound bed with a dwell time of 10 minutes, followed by continuous negative pressure at -125 mmHg for 2 to 3.5 hours. Dressing changes occurred every 2-3 days. NPWTi-d was discontinued once the wound bed was fully covered with healthy granulation tissue.
Results: Eight patients (age range 29-78 years) presented for care. Previous medical history included paraplegia, venous insufficiency, poor wound healing, and previous diagnosis of sepsis. Wound types were bilateral decubitus ulcers, venous leg ulcer, abdominal wound, and amputation. NPWTi-d was discontinued in all 8 patients after granulation tissue completely covered the wound bed.
Discussion: Use of NPWTi-d with ROCF-CC resulted in the hydromechanical removal of infectious materials, non-viable tissue, and wound debris, leading to the development of healthy granulation tissue in the wound bed for all 8 patients.