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Case Series/Study
Historically, chronic wounds are treated with various topical therapies. The goals of topical wound management including supporting tissue repair, preventing infection, reducing pain, eliminating devitalized tissue, creating a moist environment, and decreasing edema. Clinical studies typically focus on the effectiveness of a singular treatment. The objective of this retrospective case series is to investigate chronic wound progress when continuous topical oxygen therapy (cTOT) device was used in combination with cellular, acellular and matrix-like products (CAMPs).
Methods:
A single center retrospective analysis was conducted to examine the outcomes of chronic wound combination therapy consisting of cTOT and CAMPs. Four patients were included in this case study. Demographic and wound-specific details were recorded without any patient identifying data.
Results:
Four male subjects with an average age of 69 years were identified in this case review. The mean wound area reduction seen in this patient cohort undergoing combination therapy with cTOT and CAMPs at 8 weeks was 91.25%. All went on to complete wound resolution by week 12.
Discussion:
The authors believe that this combination of topical methods might have synergistic effects and improve wound healing, and the results of this study support this assumption. With looming limitations in the number of CAMP applications permitted under various LCD/LCA policies, as well as the constraints in accessing certain CAMPs, finding innovative methods to improve wound healing will have a great value across all clinical settings.